![](https://d1htlas1ystcvb.cloudfront.net/securities/527/0ebbc638f2c731b88ece5e9281b369149336156d.jpg)
L&G Pharma Breakthrough
(BIGT)
£8.20
Previous business day’s close price
+£0.88 (+12.05%)
max available period
£6.58
£10.12
30 Jan 18
25 Jul 24
Details
This ETF tracks companies involved in the development and manufacturing of so‑called ‘orphan drugs’, via the Solactive Pharma Breakthrough Value index. Orphan drugs refers to medication that target very rare diseases. This ETF reinvests income.
Ticker: BIGT
ISIN: IE00BF0H7608
Ticker: BIGT
ISIN: IE00BF0H7608
Key information
ETF Breakdown
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2045/d21ee98746c8bbd7a7e6e738c2671d2cf500dd66.png)
Alnylam Pharmaceuticals Inc
3.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/15639/7ca062685cd5b53a5eb18ae130e3278d38f190ca.png)
United Therapeutics Corp
3.3%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/7513/e02ae9b48da7bd098415df168da5afbeed69d1c1.png)
Halozyme Therapeutics Inc.
3.1%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/10889/91c2106567fd87597a5380e7a40fc8c1f8506d3c.png)
Pharmamar S.A.
3.0%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/8389/099b1caf1b3bf86faf279a1467ea0e1c64edd0e5.png)
Biocryst Pharmaceuticals Inc.
2.9%
Bavarian Nordic A/S
2.8%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/85/778b2edc59ec2fb77796996f41b4e101b322c916.png)
Astrazeneca plc
2.8%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/4419/579fa2e83680354007ead22441e7516447eb77f6.png)
Daiichi Sankyo Co., Ltd.
2.7%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/1649/fdca1ade0333b26298bd832c6770ccd24ce81586.png)
Vertex Pharmaceuticals, Inc.
2.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/6461/b66580b374757f124c9f361381bd847db9e5286a.png)
CSL Ltd.
2.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/10781/52dffe61c41edcabd14f18911de347087e9e26bc.png)
Idorsia Ltd
2.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/6765/d161b73cab30c24a1ea4c3f0c2819785e6683c54.png)
Sarepta Therapeutics Inc
2.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2211/879e744661f8305677cd86e3cfd151db3040453b.png)
Incyte Corp.
2.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/881/561516b9a619ed3f90cb5b83f3f19b65507d176a.png)
Ipsen
2.5%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/81/4945ff933009d69c9ec018cf621340b5591c31dd.png)
Novartis AG
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/7431/3447b3d68f658afb4a771aad69cc47e8585a9995.png)
Ionis Pharmaceuticals Inc
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2597/fedaf8aae5d61684911c3d94f408f7f7c80eea0e.png)
Swedish Orphan Biovitrum AB
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/657/a94a7674b721c16352682efca4efb1117ac63acc.png)
Grifols SA
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2917/c2b7ef99bc801b69390ba83345a0a8513155e954.png)
Innovent Biologics Inc
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/4483/0bc6b58f2db764c51e475c9ec5cf8bd55023aa56.png)
Eisai Co Ltd
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/4611/f0b921f404a4e011261e8ddd0e0a7c18dd7874f1.png)
Kyowa Kirin Co. Ltd.
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/1657/bde837b1cac8b22150574c6cbc4641573fa7b718.png)
Biogen Inc
2.4%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/857/bf647faeb9407c119054928158c575eea01d3947.png)
Recordati Industria Chimica e Farmaceutica SpA
2.3%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/17305/efaafbba32a0aec9732d5565851f579df3c98c97.png)
Merck & Co Inc
2.3%
Zeria Pharmaceutical Co. Ltd.
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/1505/dbcb38eb35107e8b98edf1722b53e71d4f72b1a3.png)
Johnson & Johnson
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2325/358a25f6ec83a7e5fbe731188b32f51c4ddccb79.png)
Biomarin Pharmaceutical Inc.
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2919/f319711aab79fd4906ec87a775e1866bb6d8480d.png)
Sino Biopharmaceutical Ltd.
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/12985/a636042dfa1348bf3907eb360ceea2fcacc5fe2e.png)
Royalty Pharma plc
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/4453/b3723de9eb6aeca6bf2857cdd3ba522224fbea4e.png)
Chugai Ro Co Ltd
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/4405/2f7fb1bf8f119633db82fcdc0207477b4e94783c.png)
Takeda Pharmaceutical Co
2.2%
Kissei Pharmaceutical Co. Ltd
2.2%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2855/01ec4f82ccacfa7da0314aa684b2cb35bdd594ac.png)
BeiGene Ltd
2.1%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/303/64f7eb4fc62ebee3a9d0ca6911b26542db2f1f6a.png)
Genmab
2.1%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/2427/270dd77097a26e2c4d9f06e4bb526d4da2433642.png)
Jazz Pharmaceuticals plc
2.1%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/13441/97377628388e4275d621bc6b419fab0bb5b9ddac.png)
Beijing Innocare Pharmaceutical Technology Co Ltd
2.1%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/8049/b26630fc13379b04eca818a3aaf291c9ef5f22d9.png)
Xencor Inc
1.9%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/7451/d3c407b87511c7bb3b6c7b8b3213db99bfe66133.png)
Ultragenyx Pharmaceutical Inc.
1.9%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/10903/1696972c0af781d5840d441976f0965e6686bbf2.png)
Bluebird bio Inc
1.7%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/4805/7e89e239b50a47c66d169052b4f0583a89cecdbb.png)
Nippon Shinyaku Co. Ltd.
1.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/7247/8f341d2177b6e298b95d058c427075c7e7d70be9.png)
JCR Pharmaceuticals Co. Ltd.
1.6%
![](https://d1htlas1ystcvb.cloudfront.net/organisations/7993/95124cc351ee3b7029f48cddff542701ce5c85a9.png)
Apellis Pharmaceuticals Inc
1.4%
Others
0.2%
No holdings found.
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Please try a different search.
North America
41.2%
Europe ex‑UK
22.0%
Japan
17.1%
Asia ex‑Japan
4.8%
Emerging Markets
4.5%
UK
2.8%
Rest of the World
7.4%
Healthcare
52.9%
Technology
6.5%
Financial
5.0%
Industrial
3.1%
Sector ‐ Other
32.4%
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